The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V54250 | Peritassine A | 262601-67-2 | Peritassine A is an alkaloid extracted from Tripterygium wilfordii Hook. |
|
V3323 | PF-3450074 | 1352879-65-2 | PF-3450074 (also known as PF74) is a HIV-1 capsid-targeting small molecule antiviral compound which directly binds to the capsid (CA) protein at a site also utilized by host cell proteins CPSF6 and NUP153. |
|
V40998 | Pirmitegravir (STP0404) | 2245231-10-9 | Pirmitegravir is a potent, first-in-class allosteric integrase (ALLINI) inhibitor that targets the LEDGF/p75 binding site. |
|
V53411 | PMEDAP | 113852-41-8 | PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. |
|
V61141 | Pol (476-484), HIV-1 RT Epitope | 139079-41-7 | Pol (476-484), HIV-1 RT Epitope is a biologically active peptide. |
|
V54244 | PYR01 | 2560576-15-8 | PYR01 is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. |
|
V52957 | Reverse transcriptase-IN-1 | 2380001-43-2 | Reverse transcriptase-IN-1 (Compound 12z), a diarylbenzopyrimidine (DABP) analogue, is a potent, orally bioactive HIV-1 non-nucleoside reverse transcriptase inhibitor. |
|
V78489 | Reverse transcriptase-IN-3 | Reverse transcriptase-IN-3 is a pyrimidine-5-carboxamide analogue and an inhibitor (blocker/antagonist) of HIV-1. | |
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V80182 | Reverse transcriptase-IN-4 | Reverse transcriptase-IN-4 (compound F10) is a potent and specific non-nucleoside reverse transcriptase (NNRT) inhibitor (antagonist) with EC50 of 0.053 μM against wild-type HIV-1 and against HIV-1 mutant strains. | |
|
V54292 | Rhuscholide A | 944804-58-4 | Rhuscholide A is a benzofuran lactone with significant anti-HIV (Human Immunodeficiency Virus)-1 activity with EC50 of 1.62 μM. |
|
V13839 | RN-18 | 431980-38-0 | RN-18 is an HIV-1 Vif inhibitor. |
|
V8379 | Ro 24-7429 | 139339-45-0 | Ro 24-7429 (Ro247429; Ro-247429) is a novel and potent Tat (HIV-1 transactivator protein) antagonistwithanti-HIV, antifibrotic and anti-inflammatory activities. |
|
V54262 | Salvianan A | 2162956-63-8 | 1,6,11-Trimethyl-1,2-dihydrofuro[2',3':1,2]phenanthro[4,3-d]oxazole (compound 1) is a potent anti-HIV (Human Immunodeficiency Virus)-1 agent. |
|
V14330 | Saquinavir mesylate (Ro 31-8959; Invirase; Fortovase) | 149845-06-7 | Saquinavir mesylate(Ro-31-8959; Invirase; Fortovase),an HIV Protease Inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS. |
|
V80434 | Seletracetam lithium (Ucb 44212 lithium) | Seletracetam (Ucb 44212) lithium is an analogue of the antiepileptic drug Levetiracetam. | |
|
V54277 | Semzuvolimab (UB421) | 2409099-32-5 | Semzuvolimab is a murine IgG1κ antibody targeting the T cell surface antigen T4/Leu-3, p55 (CD4). |
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V36624 | Siamycin I (BMY-29304) | 164802-68-0 | Siamycin I (BMY-29304) is a 21-residue tricyclic peptide that is a secondary metabolite (SM, chemical compound) of actinomycetes. |
|
V85127 | Stachybotrylactam | 163391-76-2 | |
|
V35243 | Suvizumab (KD-247) | 914257-21-9 | Suvizumab (KD-247) is a neutralizing antibody against HIV-1. |
|
V76176 | TAT (47-57) GGG-Cys(Npys) | 1231898-26-2 | TAT (47-57) GGG-Cys(Npys) is a cell-penetrable peptide (CPP). |
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