The acquired immunodeficiency syndrome (AIDS), a condition in which the immune system gradually fails and life-threatening opportunistic infections and cancers proliferate, is brought on by the lentivirus (a subgroup of retrovirus) known as HIV. HIV infection happens when blood, semen, vaginal fluid, pre-ejaculate, or breast milk are shared. HIV can be found in these bodily fluids as both free virus particles and as a virus inside infected immune cells.Important immune system components like helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells are all infected by HIV. Apoptosis of uninfected bystander cells, direct viral killing of infected cells, and killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells are some of the mechanisms by which HIV infection results in low levels of CD4+ T cells. Cell-mediated immunity is lost and the body becomes progressively more vulnerable to opportunistic infections when CD4+ T cell counts fall below a critical threshold.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76172 | TAT (47-57), FAM-labeled | 1676104-81-6 | TAT (47-57), FAM-labeled is a cell-penetrable peptide (CPP). |
|
V81516 | TAT (48-57) (TFA) | TAT (48-57) (TFA) is a cell membrane-permeable (penetrable) polypeptide extracted from amino acid (AA) residues 48-57 of the HIV-1 transactivator (Tat) transcription protein. | |
|
V76454 | TAT peptide | TAT peptide is a cell-penetrating/penetrable peptide (GRKKRRQRRRPQ) developed from HIV-1 reverse transcription activator (Tat). | |
|
V76453 | TAT peptide TFA | TAT peptide (TFA) is a cell-penetrating/penetrable peptide (GRKKRRQRRRPQ) developed from HIV-1 reverse transcription activator (Tat). | |
|
V81523 | TAT-GluR23A Fusion Peptide | TAT-GluR23A Fusion Peptide is a biologically active peptide. | |
|
V81530 | TAT-NSF700scr | TAT-NSF700scr contains the complete TAT domain and glycine linker, followed by randomly arranged NSF amino acid (AA)s. | |
|
V81546 | TC14012 TFA | TC14012 TFA is a serum-stable analogue of T140 and a selective CXCR4 antagonist (inhibitor) with IC50 of 19.3 nM. | |
|
V3503 | Temsavir | 701213-36-7 | Temsavir (formerly known as BMS626529; BMS-626529) is a novel, potent attachment inhibitor that targetsHIV-1gp120 and prevents its binding to CD4+T cells. |
|
V53235 | Tenofovir diphosphate disodium (TFV-DP disodium) | 2738719-07-6 | Tenofovir diphosphate disodium is an antiviral reverse transcription agent and inhibitor of DNA polymerase. |
|
V16066 | Tenofovir exalidex (CMX-157) | 911208-73-6 | Tenofovir exalidex (formerly known as HDP-Tenofovir and CMX-157) is a novel and potent lipophilic / acyclic nucleoside phosphonate that is able to deliver high concentrations of the active antiviral agent tenofovir to target cells. |
|
V54264 | Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium | 2611373-74-9 | Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) displays longer t1/2 values than tenofovir in human liver microsomes, has potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. |
|
V54269 | Tenofovir-C3-O-C15-CF3 ammonium | 2611373-80-7 | Tenofovir-C3-O-C15-CF3 (ammonium) displays longer t1/2 values than tenofovir in human liver microsomes, has potent anti-HIV activity in vitro, and enhances pharmacokinetic properties in vivo. |
|
V54247 | Teropavimab (3BNC117-LS; GS-5423) | 2417213-72-8 | Teropavimab (3BNC117-LS) is an antibody. |
|
V54253 | Tifuvirtide (T-1249) | 251562-00-2 | Tifuvirtide (T-1249) is a bioactive peptide human immunodeficiency virus type 1 (HIV-1) fusion inhibitor. |
|
V35196 | Tigloylgomisin P (crotonylgomisin P) | 69176-51-8 | Tigloylgomisin P is a lignin with anti-HIV (Human Immunodeficiency Virus) activity with EC50 of 37 μM. |
|
V50921 | TN-14003 | 368874-31-1 | anti-HIV peptide |
|
V53221 | Trecovirsen (GEM91) | 153021-75-1 | Trecovirsen (GEM91) is an antisense oligonucleotide targeting the HIV gag gene. |
|
V52922 | Trovirdine (Travirdine; LY300046) | 149488-17-5 | Trovirdine inhibits HIV-1 reverse transcription with IC50 of 7 nM. |
|
V54284 | Tsugafolin | 66568-97-6 | Tsugafolin (compound 4) is a dehydroflavone with weak anti-HIV activity (IC50=118 μM) and no cytotoxic effect (<150 μM). |
|
V85029 | Uncaric acid (6β,19α-Dihydroxyursolic acid) | 123135-05-7 |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
