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Reactive Oxygen Species

Reactive Oxygen Species

Reactive oxygen species (ROS) are radical and non-radical oxygen species produced by the partial reduction of oxygen, including superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•). Endogenous ROS are produced by cells during their normal oxidative metabolism in the mitochondria as well as when they react to xenobiotics, cytokines, and bacterial invasion.

By directly inhibiting MAPK phosphatases, ROS also activates MAPK pathways. Through PTEN, ROS produced by growth factor stimulation are capable of reversibly controlling the redox state of the PI3K pathway. The cellular response to ROS may involve the activation of autophagy.

Reactive Oxygen Species related products

Structure Cat No. Product Name CAS No. Product Description
(+)-Schisandrin B ((+)-Schisandrin B) V72941 (+)-Schisandrin B ((+)-Schisandrin B) 82467-52-5 (+)-Schisandrin B is an enantiomer of Schisandrin B.
(-)-Lyoniresinol 9'-O-glucoside V72973 (-)-Lyoniresinol 9'-O-glucoside 143236-02-6 (-)-Lyoniresinol 9'-O-glucoside is an inhibitor (blocker/antagonist) of ROS.
(E/Z)-GSK5182 V67649 (E/Z)-GSK5182 2699724-40-6 (E/Z)-GSK5182 is the racemate of (E)-GSK5182 and (Z)-GSK5182.
(E/Z)-MCB-613 V88532 (E/Z)-MCB-613 296792-62-6 (E/Z)-MCB-613 is a pan-steroid receptor coactivator (SRC) stimulator.
(±)-Carnitine-d9 chloride (DL-Carnitine-d9 (chloride)) V72906 (±)-Carnitine-d9 chloride (DL-Carnitine-d9 (chloride)) 1219386-75-0 (±)-Carnitine-d9 (chloride) is the deuterated form of (±)-Carnitine chloride.
(±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) V72939 (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) 69097-97-8 (±)-Liquiritigenin ((±)-4',7-Dihydroxyflavanone) was extracted from Angelica keiskei, a cold-resistant perennial herb of the Apiaceae family.
1,3-Diphenylisobenzofuran (DPBF) V67090 1,3-Diphenylisobenzofuran (DPBF) 5471-63-6 1,3-Diphenylisobenzofuran (DPBF) is used as a selective probe for the detection and quantification of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS).
1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc V97444 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc 1287795-07-6 1-Palmitoyl-2-pyropheophorbide a-sn-glycero-3-pc is a phospholipid-porphyrin polymer.
1-甲氧基-5-甲基酚嗪鎓硫酸甲酯盐 V29766 Methoxy-PMS 65162-13-2 Methoxy-PMS (1-Methoxy PMS) is a stable electron transport intermediary.
2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside V72945 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside 1447969-66-5 2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside compound in Lilium brownie var.
2,4,7-Trihydroxy-9,10-dihydrophenanthrene V72921 2,4,7-Trihydroxy-9,10-dihydrophenanthrene 70205-52-6 2,4,7-Trihydroxy-9,10-dihydrophenanthrene is a dihydrophenanthrene analogue that can be found in Pholidota chinensis Lindl.
2-Selenouracil V72904 2-Selenouracil 16724-03-1 2-Selenouracil is an effective photosensitizer used in photodynamic therapy.
3′-Hydroxy-4′-O-methylglabridin V72965 3′-Hydroxy-4′-O-methylglabridin 175554-11-7 3′-Hydroxy-4′-O-methylglabridin is an antioxidant that effectively prevents NADH-dependent peroxidation.
3-Demethylcolchicine V72896 3-Demethylcolchicine 7336-33-6 3-Demethylcolchicine is a metabolite of colchicine.
3-Methoxy-9H-Carbazole V88404 3-Methoxy-9H-Carbazole 18992-85-3 3-Methoxy-9H-Carbazole induces increased caspase-3 activity and the generation of reactive oxygen species.
4-Methyl-6-phenyl-2H-pyranone V72955 4-Methyl-6-phenyl-2H-pyranone 4467-30-5 4-Methyl-6-phenyl-2H-pyranone may be utilized to prepare N-hydroxypyridone analogues that protect astrocytes from hydrogen peroxide-induced toxicity by improving mitochondrial function.
5-Hydroxyoxindole V72910 5-Hydroxyoxindole 3416-18-0 5-Hydroxyoxindole is a structural analog of uric acid.
5-氨基酮戊酸甲酯盐酸盐 V5169 Methyl aminolevulinate HCl (LS-187769) 79416-27-6 Methyl-5-aminolevulinate HCl, a prodrug that is metabolised to Protoporphyrin IX (sensitizer) used in photodynamic therapy, is a used as a topical cream formulation which contains the hydrochloride salt of methyl-5-aminolevulinate, a lipophilic methyl ester of 5-aminolevulinic acid, with photosensitizer prodrug activity.
5-羟基-7,8-二甲氧基黄酮 V34285 Moslosooflavone 3570-62-5 Moslosooflavoneone is a natural flavonoid extracted from Andrographis paniculata.
6-Deoxyjacareubin V72954 6-Deoxyjacareubin 16265-56-8 6-Deoxyjacareubin is a natural xanthone extracted from the leaves of Vismia latifolia.
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