Drug metabolites are created when a drug is metabolized into a different form that still has therapeutic effects. Active metabolites can be produced by drug metabolism redox reactions like heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations. In some rare circumstances, conjugation reactions can also produce an active metabolite.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V76525 | Seco Rapamycin ethyl ester | Seco Rapamycin ethyl ester is the open-ring metabolite of Rapamycin. | |
|
V76496 | Sofosbuvir impurity B (sofosbuvir impurity B) | Sofosbuvir impurity B is an impurity in Sofosbuvir. | |
|
V76495 | Sofosbuvir impurity D | Sofosbuvir impurity D is an impurity in Sofosbuvir. | |
|
V76494 | Sofosbuvir impurity E (sofosbuvir impurity E) | Sofosbuvir impurity E is an impurity in Sofosbuvir. | |
|
V72199 | T-705RMP | 356783-08-9 | T-705RMP is the phosphorylated metabolite of T-705 and has a weak inhibitory effect on host cell IMP dehydrogenase (IMPDH) activity, with IC50 of 601 μM. |
|
V72156 | Tamoxifen N-oxide | 75504-34-6 | Tamoxifen N-oxide is a metabolite of Tamoxifen. |
|
V72167 | Terbuthylazine-desethyl (Desethylterbuthylazine) | 30125-63-4 | Terbuthylazine-desethyl (Desethylterbuthylazine) is the chlorodealkylated metabolite of Terbuthylazine (triazine herbicide). |
|
V72105 | Teriflunomide (teriflunomide; A77 1726) | 163451-81-8 | Teriflunomide (A77 1726) is the bioactive metabolite of leflunomide and may be used in rheumatoid arthritis research. |
|
V72130 | Tetrachlorocatechol | 1198-55-6 | Tetrachlorocatechol is a metabolite of pentachlorophenol. |
|
V72161 | Tetrachlorohydroquinone (TCHQ; Tetrachloroquinol) | 87-87-6 | Tetrachlorohydroquinone (TCHQ) is a metabolite of pentachlorophenol. |
|
V72245 | Threo-dihydrobupropion | 153365-82-3 | Threo-dihydrobupropion is the major metabolite of bupropion, formed through oxidation and reduction, and has pharmacological activity. |
|
V72274 | Threo-dihydrobupropion hydrochloride | 357637-18-4 | Threo-dihydrobupropion HCl is the primary metabolite of bupropion and may be used in depression, behavioral and biochemical studies. |
|
V72168 | Tianeptine metabolite MC5 sodium salt (tianeptine metabolite MC5 sodium salt) | 115220-11-6 | Tianeptine metabolite MC5 sodium salt is the main bioactive metabolite of tianeptine. |
|
V72149 | Trimethoprim 3-oxide (Trimethoprim 3-N-oxide) | 27653-67-4 | Trimethoprim 3-oxide is a primary metabolite of trimethoprim. |
|
V72272 | Trityl olmesartan medoxomil impurity III (olmesartan impurity 27) | 1227626-51-8 | Trityl olmesartan medoxomil impurity II is an impurity in Trityl olmesartan medoxomil. |
|
V27881 | Urolithin A | 1143-70-0 | Urolithin A isa microbial metabolite of ellagic acidin the gut and an inducer of mitophagy. |
|
V72227 | Venetoclax N-oxide | 2469279-00-1 | Venetoclax N-oxide is an impurity of Venetoclax. |
|
V72104 | Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) | 117675-21-5 | Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. |
|
V72116 | Zidovudine O-β-D-glucuronide sodium (3'-Azido-3'-deoxythymidine β-D-glucuronide sodium) | 133525-01-6 | Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. |
|
V72212 | Zolmitriptan N-Oxide | 251451-30-6 | Zolmitriptan N-Oxide is the major metabolite of Zolmitriptan. |
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