|
V4205
|
Amicarbazone
|
129909-90-6 |
Amicarbazone (also known as BAY-MKH3586 and BAY314666) is a novel, potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); Amicarbazone is a new triazolinone herbicide with a broad spectrum of weed control. |
|
V4243
|
AZD6482 S-isomer
|
1173900-37-2 |
AZD6482 S-isomer, is an isomer of AZD6482 which is a novel, potent, selective and ATP competitive PI3Kβ inhibitor with IC50 of 10 nM, 8-, 87- and is 109-fold more selective to PI3Kβ than PI3Kδ, PI3Kα and PI3Kγ in cell-free assays. |
|
V4171
|
BAY-524
|
1445830-39-6 |
BAY-524is a novel and potent Bub1 inhibitor with anIC50of 450 nM for human Bub1 in the presence of 2 mM ATP. |
|
V4168
|
BAY-598 R-isomer
|
1906920-28-2 |
BAY-598 R-isomer (R-BAY598) is the R-enantiomer of BAY589 which is a peptide-competitive SMYD2 inhibitor with antineoplastic activity. |
|
V4164
|
BAY-677
|
2117404-84-7 |
BAY-677 is an inactive and negative control for BAY-678. |
|
V4129
|
BLU-782
|
2141955-96-4 |
BLU-782 has been discontinued. |
|
V4273
|
Bucladesine (Dibutyryl-cAMP)
|
362-74-3 |
Bucladesine (DC2797; DC-2797; Dibutyryl-cAMP) is a potent and cell-permeable PKA activator and a cAMP analog that mimics the action of endogenous cAMP. |
|
V4136
|
Dioctyl decanedioate
|
2432-87-3 |
Dioctyl decanedioate (decadioic acid, dioctyl ester; Decanedioic acid, dioctyl ester; decanedioicaciddioctylester; Dioctyl-1,10-decanedioate) is a biochemical. |
|
V4161
|
Diroximel fumarate
|
1577222-14-0 |
Diroximel fumarate (also known as ALKS 8700) is a novel compound that is taken orally and rapidly converted into monomethyl fumarate (MMF). |
|
V4210
|
Emiglitate
|
80879-63-6 |
Emiglitate (also known as BAY o 1248) is a novel, potent, selective and competitive inhibitor ofα-glucoside hydrolase. |
|
V4148
|
Fenebrutinib (GDC-0853) HCl
|
2128304-54-9 |
Fenebrutinib HCl (formerly known RG-7845; GDC-0853 hydrochloride) is an orally bioavailable, and noncovalent (reversible) brutons tyrosine kinase (BTK) inhibitor (Ki = 0.91 nM) with anticancer and anti-inflammatory activity. |
|
V4137
|
GSK-2336805
|
1256390-53-0 |
GSK-2336805 (also known as GSK-805; GSK2336805; JNJ-56914845) is a novel and potent inhibitor of HCV NS5A. |
|
V4046
|
Irosustat
|
288628-05-7 |
Irosustat (formerlyknown as STX64, BN83495 or 667 coumate) is a novel potent and irreversibleinhibitor of steroid sulfatasewith anIC50of 8 nM and has the potential for treating breast cancer. |
|
V4075
|
LGD-4033
|
1165910-22-4 |
LGD-4033 (also known as VK-5211 and Ligandrol) isa novel, potent and selective androgen receptor modulator (SARM) and is being investigated by Ligand Pharmaceuticals for treatment of conditions such as muscle wasting and osteoporosis. |
|
V4291
|
MK-6240
|
1841078-87-2 |
MK-6240 is a novel positron emission tomography (PET) tracer fordetecting neurofibrillary tangles (NFTs). |
|
V4015
|
ML-290
|
1482500-76-4 |
ML-290, a 2-acetamido-N-phenylbenzamide analog, is a novel potent, selective and orally bioactive agonist of the relaxin/insulin-like family peptide receptor (RXFP1)and an activator of anti-fibrotic genes with anEC50of 94 nM. |
|
V4010
|
ML-7
|
109376-83-2 |
ML-7 (ML7) is a potent Myosin light chain kinase (MLCK) inhibitor with IC50of 300 nM and IC50>10 μM for MLCK and TRPC6 channel respectively. |
|
V4023
|
ML132
|
1230628-71-3 |
ML132 (also known as NCGC 00185682) is a potent and selectivecaspase 1inhibitor with anIC50of 0.316 nM. |
|
V4225
|
NSC 77674
|
737-86-0 |
NSC77674 (also known as PIH or Pyridoxal isonicotinoyl hydrazone) is is a novel, potent, lipophilic, nontoxic, iron-chelating agent that shows high iron chelation efficacy both in vitro in cell culture models and in vivo in rats and mice. |
|
V4132
|
PROTAC-VHL-ligand
|
1448297-52-6 |
PROTAC-VHL-ligand or Protein degrader 1 is a novel and potent small molecule ligand forVHL (Von Hippel-Lindau), anE3 ligasewhich has been targeted by many PROTACs (proteolysis-targeting chimeras) degarders. |