|
V1087
|
ADX-47273 (BA 94673139)
|
851881-60-2 |
ADX47273 (ADX-47273;BA-94673139;BA94673139)is a potent, selectiveand specific mGlu5 positive allosteric modulator(PAM) with important biological activity. |
|
V33762
|
CNQX
|
115066-14-3 |
CNQX (FG9065; FG-9065; 6-cyano-7-nitroquinoxaline-2,3-dione)is an AMPA/kainate antagonist that inhibits AMPA and kainate receptors with IC50values of 0.3 μM, 1.5 μM, respectively. |
|
V1084
|
CTEP (RO4956371)
|
871362-31-1 |
CTEP (also called RO4956371; RO 4956371;RO-4956371) is a long-acting and orally bioavailable allosteric antagonist of metabotropic glutamate receptor 5 (mGlu5) receptor with important biological activity. |
|
V1982
|
D-glutamine
|
5959-95-5 |
D-glutamine (also known as H-D-Gln-OH), an unnatural isomer of glutamine, is a D type stereoisomer of glutamine which is one of the 20 amino acids encoded by the standard genetic code. |
|
V11432
|
AP-5
|
76326-31-3 |
AP-5 (AP5) is a novel, selective and potent NMDA (N-methyl-D-aspartate) receptor antagonist with anticonvulsant activity. |
|
V2710
|
Evans Blue
|
314-13-6 |
Evans Blue (Direct Blue 53)is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, it is also an AMPA/kainate receptor antagonist. |
|
V1088
|
IEM 1754 2HBr
|
162831-31-4 |
IEM 1754 2HBr (IEM-1754; IEM 1754; IEM1754), the dihydrobromide salt ofIEM-1754, is a selective voltage-dependent open-channel blocker of AMPA/kainate receptorswith important biological activity. |
|
V1086
|
NMDA (N-Methyl-D-aspartic acid)
|
6384-92-5 |
NMDA (N-Methyl-D-aspartic acid; LC488A; LC488 A;LC488-A; LC 488A; LC-488A) is an aspartic acid analog withan N-methyl substituent and D-configuration and a glutamate-like excitatory chemical substance. |
|
V1079
|
Pomaglumetad (LY404039)
|
635318-11-5 |
Pomaglumetad (LY404039; LY-404039; LY-404,039; LY404,039) is a novel and potent agonist of recombinant human mGlu2/mGlu3 receptors with the potential for the treatment of Schizophrenia. |
|
V23963
|
Ro 25-6981 free base
|
169274-78-6 |
Ro 25-6981 is a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. |
|
V1090
|
VU 0357121
|
433967-28-3 |
VU0357121 (VU-0357121, VU 0357121) is a positive allosteric modulator (PAM) of mGlu5 (metabotropic glutamate receptor 4) with antiparkinsonian-like effects. |
|
V1092
|
VU 0361737
|
1161205-04-4 |
VU 0361737 (VU0361737; VU-0361737) is a novel, brain-penetrable and selective positive allosteric modulator (PAM) for mGlu4 receptor with important biological activity. |
|
V1085
|
VU 0364439
|
1246086-78-1 |
VU 0364439 (VU0364439; VU-0364439) is a mGlu4 (metabotropic glutamate receptor 4) positive allosteric modulator (PAM) with important biological activity. |
|
V1091
|
VU 0364770
|
61350-00-3 |
VU 0364770 (VU-0364770, VU0364770) is a potent positive allosteric modulator (PAM) of mGlu4 (metabotropic glutamate receptor 4) with anti-parkinsonian-likeactivity. |
|
V1094
|
Piracetam (UCB-6215)
|
7491-74-9 |
Piracetam (BRN-1526393;UCB-6215; Cl-871;Breinox;Ciclofalina;Euvifor; Gabacet; Nootron)is a cyclized derivative of the neurotransmitter gamma-aminobutyric acid (GABA) that has been approved for use in the treatment of a wide range of cognitive disorders. |
|
V1078
|
Riluzole (RP-54274, PK 26124)
|
1744-22-5 |
Riluzole (formerly PK26124, RP54274, RP-54274, PK-26124;Rilutek),an anticonvulsant of the Na+channelblocker class, is a glutamate release inhibitor with neuroprotective, anticonvulsant, anxiolytic and anesthetic activities. |
|
V1081
|
(-)-Dizocilpine Maleate [(-)-MK 801 maleate]
|
121917-57-5 |
DizocilpineMaleate [also known as (-)-MK-801; MK801; MK 801], the maleate salt ofdizocilpine, is anovel, potent, selective and non-competitiveN-methyl-D-aspartate (NMDA) receptor antagonist with potential to treat awide range of neurodegenerative conditions or disorders in which NMDA receptors play an important role. |
|
V5684
|
Dizocilpine (MK-801)
|
77086-21-6 |
Dizocilpine (MK-801), is a novel, potent, selective and non-competitive NMDA (N-Methyl-D-aspartate) receptor antagonist with Kd of 37.2 nM in rat brain membranes. |
|
V7337
|
CX-516
|
154235-83-3 |
CX516 (BDP 12) is a positive regulator of AMPA receptors and may be utilized in study/research of Alzheimer's disease (AD), schizophrenia, etc. |
|
V1089
|
MPEP
|
96206-92-7 |
MPEP is a highly potent, selective, and non-competitive antagonist of mGlu5 receptor with anti-anxiolytic/antidepressant activity. |