Glycoside hydrolase enzymes are glucosidases. A glucosidase that works on α(1→4) bonds is called α-glucosidase, and it is found in the small intestine's brush border. α-Glucosidase inhibitors are a new class of diabetes medications. It can effectively control blood sugar levels and prevent diabetic complications by lowering the postprandial blood sugar concentration.
In β-D-glucosides and oligosaccharides, β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues, releasing glucose in the process. Because of its crucial function in the breakdown of cellulose, the transformation of glycosides, and numerous other industrial processes, β-glucosidase has garnered a great deal of interest from the scientific community. In order to degrade cellulose, β-glucosidases are crucial because they catalyze the last stage of cellulose hydrolysis.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V84809 | (E)-p-Coumaramide | 194940-15-3 | |
|
V87473 | (S)-N-(1H-Indole-3-acetyl)tryptophan | 57105-53-0 | (S)-N-(1H-Indole-3-acetyl)tryptophan (compound 4a) is a tryptophan derivative that weakly inhibits β-D-glucosidase. |
|
V85669 | 1'-O-Methyl neochebulinate | 1236310-34-1 | |
|
V32050 | Duvoglustat (1-Deoxynojirimycin) | 19130-96-2 | Duvoglustat (Moranoline; deoxynojirimycin;1-Deoxynojirimycin;AT-2220; DNJ) is a novel and potent alpha-glucosidase inhibitorfound in mulberry leaves and hasantihyperglycemic, anti-obesity, and antiviral activities. |
|
V87306 | 2,3-Dihydrocalodenin B | 2,3-Dihydrocalodenin B (Compound 6) is a compound isolated from Knema globularia. | |
|
V87451 | 2-Hydroxyquinoline | 59-31-4 | 2-Hydroxyquinoline is a potent inhibitor of α-glucosidase with IC50 values of 64.4 and 130.5 µg/mL for α-glucosidase and α-amylase, respectively. |
|
V87472 | 9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one | 204134-70-3 | 9-(4′-Hydroxyphenyl)-2-methoxyphenalen-1-one is a phytoalexin and a mixed-competitive α-glucosidase inhibitor of Bacillus stearothermophilus (IC50: 3.86 mg/L). |
|
V84590 | AChE/BChE-IN-17 | ||
|
V84506 | Afegostat tartrate (AT 2101; D-Isofagomine tartrate; Isofagomine tartrate) | 919364-56-0 | |
|
V87299 | Antidiabetic agent 5 | 2152667-21-3 | Antidiabetic agent 5 (compound S1) is an antidiabetic agent. |
|
V87475 | Arisanschinin D | 1314021-69-6 | Arisanschinin D (Ananonin B) is an α-Glucosidase inhibitor isolated from Schisandra arisanensis Hay. |
|
V51240 | Chrysin 6-C-arabinoside 8-C-glucoside | 185145-33-9 | Chrysin 6-C-arabinoside 8-C-glucoside is an α±-glucosidase inhibitor that is extensively used in type 2 diabetes research. |
|
V2298 | CID-4694321 | 1462267-08-8 | CID-4694321 (also known as ML-266; ML266;CID-4694321) is a novel and potent activator of GCase (glucocerebrosidase) with the potential to be used for treatingGaucher disease. |
|
V87457 | CTL26 | CTL26 is a potent and orally active α-glucosidase inhibitor with IC50 of 2.81 µM. | |
|
V84734 | Gcase activator 3 | 2270984-21-7 | |
|
V51015 | GI-570310 | 301210-82-2 | a-glucosidase inhibitor |
|
V87476 | Granatin B | 77322-54-4 | Granatin B is a known compound isolated from pomegranate flowers. |
|
V51868 | Leucosceptoside A | 83529-62-8 | Leucosceptoside A is a phenylethanol glycoside with antihyperglycemic and antihypertensive activities. |
|
V24463 | LTI-291 | 1919820-28-2 | Gcase activator 1 is an activator of glucocerebrosidase (Gcase). |
|
V88494 | MPO-IN-6 | MPO-IN-6 (compound ADC) is an electrophilic agent with good antioxidant and anti-inflammatory properties. |
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