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V1163
|
Fesoterodine Fumarate
|
286930-03-8 |
Fesoterodine Fumarate (SPM907; Toviaz, SPM-907), the fumarate salt of Fesoterodine which is a prodrug of 5-hydroxymethyl tolterodine, is a muscarinic AChR receptor antagonist that has been approved for treating overactive bladder syndrome. |
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V1197
|
Flavoxate HCl (Rec-7-0040; DW61)
|
3717-88-2 |
Flavoxate HCl (Rec-7-0040; DW-61; NSC-114649;Rec 7-0040; Rec7-0040; DW61; NSC114649),the hydrochloride salt ofFlavoxate which is a flavanoid,is a muscarinic AChR antagonist with an IC50 of 12.2 μM. |
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V13604
|
Galanthamine
|
357-70-0 |
Galanthamine is a potent and long-acting AChE inhibitor with IC50 of 0.35 μM, it exhibits 50-fold selectivity against butyryl-cholinesterase. |
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V1204
|
Galanthamine HBr
|
1953-04-4 |
Galanthamine HBr (Razadyne, Reminyl),the hydrobromide salt ofGalanthamine, is a centrally active and long-acting AChE/acetylcholinesterase inhibitor approved for the treatment of cognitive decline in Alzheimers disease and various other memory impairments. |
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V1185
|
Gallamine Triethiodide
|
65-29-2 |
Gallamine Triethiodide (Flaxedil; Tricuran; Gallamoni jodidum; Gallaminii iodidum),a non-depolarising muscle relaxant, is a potent and cardioselective cholinergic receptor blocker with an IC50 of 68.0 ± 8.4 μM. |
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V14212
|
Glycopyrrolate
|
596-51-0 |
Glycopyrrolate (Glycopyrronium bromide, Robinul, Glycopyrrolate bromide,Gastrodyn) is an antispasmodic medication and a muscarinic antagonist used in the treatment of some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. |
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V1201
|
Hexamethonium Bromide
|
55-97-0 |
Hexamethonium Bromide (Vegolysen; Esametina; Simpatoblock),a peripherally-acting and nondepolarizing neuromuscular blocker,is a selective antagonist of neuronal-type nicotinic AChR in ganglia that wasused to treat chronic hypertension. |
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V1196
|
Homatropine Bromide (Homatropine hydrobromide)
|
51-56-9 |
Homatropine Bromide (Equipin, Isopto Homatropine), the hydrobromide salt of Homatropine, is a potent muscarinic AChR (acetylcholine receptor) antagonist used before eye examinations
(i.e. refraction), before and after certain eye surgeries, and for treating certain eye conditions (e.g., uveitis). |
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V1198
|
Homatropine Methylbromide (Homatropine methobromide)
|
80-49-9 |
Homatropine Methylbromide(Homatropine methobromide),a quaternary ammonium salt of methylhomatropine and a peripherally acting anticholinergic medication, is potent muscarinic AChR antagonist used to treat duodenal or stomach ulcers or intestine problems. |
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V1178
|
Ipratropium Bromide (Sch 1000)
|
22254-24-6 |
Ipratropium Bromide (Sch 1000; Sch1000; Atrovent, Apovent, Ipraxa, Rinatec) is a potent antagonist of M3 type muscarinic acetylcholine receptors that opens up the medium and large airways in the lungs. |
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V25120
|
Isoimperatorin
|
482-45-1 |
Isoimperatorin is a COX-2 inhibitor. |
|
V1200
|
L-Hyoscyamine (Daturine)
|
101-31-5 |
L-Hyoscyamine (Daturine), a natural tropane alkaloid and plant toxin, is the the levo-isomer of atropine and is used for controlling symptoms associated with disorders of the gastrointestinal (GI) tract. |
|
V24302
|
Lobeline hydrochloride (C-07475)
|
134-63-4 |
Lobeline hydrochloride,an alkaloid and nonstimulant medication that can alter dopamine uptake in brain,is a novel and potenta nicotinic receptor agonist and VMAT2 ligand, which stimulates dopamine release, and inhibits the reuptake of dopamine and serotonin, acting as a mixed agonist-antagonist at nicotinic acetylcholine receptors and antagonist at µ-opioid receptors. |
|
V1165
|
LY2119620
|
886047-22-9 |
LY2119620 (LY 2119620; LY-2119620) is a novel, potent, specific, high-affinity and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors, the so called positive allosteric modulator (PAM). |
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V1175
|
Methscopolamine bromide
|
155-41-9 |
Methscopolamine bromide [known also as (-)-Scopolamine methyl bromide; Hyoscine methyl bromide], a methylated scopolamine derivative, is a muscarinic acetylcholine receptor antagonist/blocker that was used to treat peptic ulcers by reducing stomach acid secretion. |
|
V1180
|
Neostigmine Bromide (Eustigmin; Neoserine)
|
114-80-7 |
Neostigmine Bromide (Eustigmin bromide; Neoserine bromide) is a reversible acetylcholinesterase inhibitor and a medication used to treat myasthenia gravis, Ogilvie syndrome, and urinary retention without the presence of a blockage. |
|
V7032
|
Neostigmine methylsulfate
|
51-60-5 |
Neostigmine methylsulfateis a parasympathomimetic compound anda reversible acetylcholinesterase inhibitor. |
|
V1166
|
Nitenpyram
|
150824-47-8 |
Nitenpyram (trade names Capstar, Bestguard),an insect neurotoxin of the neonicotinoid class, is a fast and long-acting, and orally bioavailable nicotinic acetylcholine receptor (AchR) agonist with neural signaling-blocking activity. |
|
V4121
|
Nitrocaramiphen hydrochloride
|
98636-73-8 |
Nitrocaramiphen hydrochloride is a M1 muscarinic (mAChR) antagonist which demonstrates71-foldselectivityforM1overM2. |
|
V1190
|
Orphenadrine Citrate
|
4682-36-4 |
Orphenadrine Citrate (BS-5930;BS5930; BS 5930; Disipal), the citrate salt ofOrphenadrine,is anuncompetitiveNMDA receptor antagonist and apotent skeletal muscle relaxant with antispastic and analgesic activities. |