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V1192
|
Otilonium Bromide (Octylonium bromide; SP63)
|
26095-59-0 |
Otilonium bromide (SP-63;Octylonium bromide; SP63; trade name Spasmomen among others) is a potent anti-muscarinic agent and a CCB (calcium channel blocker) used to relieve spasmodic pain of the gut, in particular in irritable bowel syndrome. |
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V1186
|
Oxybutynin
|
5633-20-5 |
Oxybutynin (Ditropan, Lyrinel XL, Lenditro,Oxybutynin, Uripan) is a potent and competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties. |
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V1193
|
Oxybutynin chloride
|
1508-65-2 |
Oxybutynin chloride (Ditropan;Ditropan XL), the hydrochloride salt of oxybutynin,is a competitive antagonist of muscarinic acetylcholine receptor subtypes M1, M2, and M3used to treat bladder and urinary conditions (i. |
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V1162
|
Pancuronium dibromide
|
15500-66-0 |
Pancuronium dibromide (OrgNA97; NA-97; Org NA 97; Pavulon),a neuromuscular relaxant used in euthanasia, is a bis-quaternary steroid and a competitive nicotinic acetylcholine receptor antagonist with an IC50 of5.5 nM. |
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V1164
|
Paroxetine HCl (BRL29060)
|
78246-49-8 |
Paroxetine HCl (formerly BRL-29060A, BRL29060A, FG7051;FG-7051),the hydrochloride salt ofParoxetine, is a potent and selective serotonin uptake inhibitor (SSRI) that is effective in the treatment of depression. |
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V1183
|
Pentoxyverine Citrate (Carbetapentane)
|
23142-01-0 |
Pentoxyverine Citrate (Loucarbate; Carbetapentane Citrate), the citrate salt ofPentoxyverine, is an agonist of the sigma-1 receptor andan antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold. |
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V1206
|
Pilocarpine HCl
|
54-71-7 |
Pilocarpine HCl (Pilocarpal;NSC-5746; Ocusert; Pilocar;Pilocar SMP; Salagen; NSC5746),the hydrochloride salt of pilocarpine,is a naturally occurring and nonselective muscarinic acetylcholine receptor agonist used to treat dry mouth caused by radiotherapy in patients with head and neck cancer and in patients with Sjogrens syndrome. |
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V1191
|
PNU-120596 (NSC-216666)
|
501925-31-1 |
PNU-120596 (PNU120596;NSC 216666;PNU 120596;NSC-216666)is a potent and selective PAM (positive allosteric modulator) of α7 nAChR (acetylcholine receptor) with an EC50 of 216 NM. |
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V14800
|
Pralidoxime iodide
|
94-63-3 |
Pralidoxime iodideis an antidote for organophosphate poisoning, acting as areactivator of acetylcholinesterase (AChE). |
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V1172
|
Pyridostigmine Bromide
|
101-26-8 |
Pyridostigmine Bromide (Mestinon; Regonol; Kalimin) is a parasympathomimetic and a reversible cholinesterase inhibitor used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants. |
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V1189
|
Rivastigmine Tartrate (ENA713; SDZ-ENA 713)
|
129101-54-8 |
Rivastigmine Tartrate (formerly ENA-713, SDZ-ENA 713; Exelon, Exelon Patch), the tartrate salt of rivastigmine, is a potent and reversible cholinesterase inhibitor used to treat mild to moderate dementia caused by Alzheimer's or Parkinson's disease. |
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V1176
|
Rocuronium Bromide (ORG 9426 Bromide)
|
119302-91-9 |
Rocuronium Bromide (ORG-9426; Zemuron; Esmeron; Esmeron; Esmerone) is a potent and competitive Nicotinic acetyl-choline receptors (AchR) antagonist, which is a non-depolarizing neuromuscular blocking agent used in anaesthesia required for surgery or mechanical ventilation. |
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V5514
|
Scopolamine
|
51-34-3 |
Scopolamine (Hyoscine) isan approved medication used to treat motion sickness and postoperative nausea and vomiting. |
|
V0034
|
Scopolamine HBr (Hyoscine)
|
114-49-8 |
Scopolamine HBr, also known as Hyoscine, is the hydrobromide salt of scopolamine which is a competitive and non-selective antagonist of muscarinic acetylcholine receptor with an IC50 of 55.3 nM. |
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V1174
|
Solifenacin succinate (YM905)
|
242478-38-2 |
Solifenacinsuccinate (formerly YM-905; YM905;Trade name: Vesikur; Vesicare), the succinate salt of solifenacin which is approved for treating overactive bladder, is a novel and potent muscarinic receptor antagonist withpKis of 7.6, 6.9 and 8.0 forM1,M2andM3receptors, respectively. |
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V1182
|
Succinylcholine Chloride Dihydrate
|
6101-15-1 |
Succinylcholine Succinylcholine Chloride Dihydrate (also called Suxamethonium Chloride Dihydrate), the dihydrate form ofSuccinylcholine Succinylcholine Chloride, is a quaternary skeletal muscle relaxant usually with anesthetic effects and is used in the form of its bromide, chloride, or iodide. |
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V9380
|
Sulfoxaflor
|
946578-00-3 |
Sulfoxaflor (GF-2372; XDE-208) is a sulfoximine-basedsystemic insecticide which acts as an agonist of nAChR1 and nAChR2. |
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V1160
|
Tiotropium Bromide hydrate (BA-679 BR)
|
139404-48-1 |
Tiotropium Bromide hydrate (PUR-0200; BA-679BR; BA679BR;PUR0200; Spiriva), the monohydrate form of tiotropium bromide, is an anticholinergic and bronchodilator and a muscarinic receptor antagonist used as a long-acting bronchodilator for the management of chronic obstructive pulmonary disease (COPD). |
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V1161
|
Tolterodine tartrate (Kabi-2234; PNU-200583E)
|
124937-52-6 |
Tolterodine tartrate (PNU-200583E; PNU200583E;Detrol LA; Detrusitol) is a tartrate salt of tolterodine that is a potent and competitive muscarinic receptor antagonist. |
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V1181
|
Tropicamide
|
1508-75-4 |
Tropicamide (formerlyRo-17683;Ro 1-7683; trade names Mydral; Mydriafair; Mydriaticum; Mydrum),an approved medication used to dilate the pupil and help with eye examination,is a potent anticholinergic and a muscarinic receptor isoform M4 antagonistwith important biological activity. |