|
V1168
|
5-hydroxymethyl tolterodine (PNU 200577)
|
207679-81-0 |
5-hydroxymethyl tolterodine (Desfesoterodine, PNU 200577,PNU-200577, 5HMT, 5HM;5-HMT, 5-HM), the active metabolite of tolterodine which is a medicationused treat overactive bladder, is a novel and potent muscarinic receptor antagonist with a Kb of 0.84 nM. |
|
V1177
|
Acetylcholine Chloride
|
60-31-1 |
AcetylcholineChloride(ACh chloride; Ovisot;TL-1505; TL-1505) is an organic chemical and a commonneurotransmitterfound in the central and peripheral nerve systemthat functions in the brain and body of many types of animals, including humans, as a neurotransmitter—a chemical released by nerve cells to send signals to other cells. |
|
V1194
|
Aclidinium Bromide (LAS 34273; LAS-W 330)
|
320345-99-1 |
Aclidinium Bromide (formerly LAS34273, LAS-W 330; brand names Tudorza Genuair;Eklira Genuair; Bretaris Genuair) is a potent, long-acting and inhalable muscarinic antagonist used as a maintenance treatment for chronic obstructive pulmonary disease (COPD). |
|
V10221
|
Acotiamide hydrochloride trihydrate (YM443; Z338)
|
773092-05-0 |
Acotiamidehydrochloride trihydrate (YM-443; Z-338) is a potent, orally bioactive and first-in-class gastroprokinetic agent for the treatment of functional dyspepsia. |
|
V6652
|
Arecoline
|
63-75-2 |
Arecoline, a naturally occurring alkaloid, is a partial agonist at nicotinic and muscarinic acetylcholine receptors. |
|
V1187
|
Arecoline HBr
|
300-08-3 |
Arecoline HBr (NSC56321, NSC-56321), the hydrobromide salt ofArecoline which is a naturally occurring alkaloid found in the betel nut of the Areca palm, is a potentagonist of muscarinic acetylcholine receptor with the potential to be used in treating dementia. |
|
V1173
|
Atropine sulfate monohydrate
|
5908-99-6 |
Atropine sulfate monohydrate (Sulfatropinol; Tropintran; Atropette; Corbella), the sulfate salt and hydrated form of atropine, is a competitive andbroad-spectrum antagonist of the muscarinic acetylcholine receptors. |
|
V1205
|
Benzethonium Chloride
|
121-54-0 |
Benzethonium chloride (Hyamine,Benzethonium Chloride, Solamine, Disilyn),a synthetic quaternary ammonium salt of Benzethonium,is a potent inhibitor of nAChRs withsurfactant, antiseptic, and anti-infective activities. |
|
V1179
|
Bethanechol chloride
|
590-63-6 |
Bethanechol Chloride (also known as Carbamyl-β-methylcholine chloride) is aparasympathomimetic choline carbamate and an analog of acetylcholine with a long duration of action due to improved metabolic stability. |
|
V17279
|
Butylscopolamine bromide
|
149-64-4 |
Butylscopolamine bromide is a potent antimuscarinic quaternary ammonium analogue acting as a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM). |
|
V17514
|
Carbachol
|
51-83-2 |
Carbachol is a cholinomimetic drug that binds and activates the acetylcholine receptor. |
|
V5661
|
Chelidonine
|
476-32-4 |
Chelidonine is an isoquinoline alkaloid found in celandine. |
|
V11209
|
Corydaline
|
518-69-4 |
Corydaline is a bioactive and naturally occurringisoquinoline alkaloid extracted fromCorydalis yanhusuo. |
|
V1169
|
Cytisine (Baphitoxine, Cytisinicline, Sophorine)
|
485-35-8 |
Cytisine (Baphitoxine,Sophorine; Citizin; HSDB-3560; Laburnin; NSC-407282;Cytisinicline),a nicotinic acetylcholine receptor agonist,is a naturally occuring alkaloid found in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. |
|
V1171
|
Darifenacin HBr (UK88525)
|
133099-07-7 |
Darifenacin HBr (formerly known as UK-88525;Emselex; Enablex),the hydrobromide salt ofDarifenacin, is a approved medication used to treat urinary incontinence and overactive bladder. |
|
V1202
|
Decamethonium Bromide
|
541-22-0 |
Decamethonium bromide (Syncurine; Decamethonum;Lopac-D-1260; (DM)Br2 Syncurine),a quaternary ammonium ion, is a short-acting, depolarizing muscle relaxant and/or neuromuscular blocker used in anesthesia to induce paralysis. |
|
V1195
|
Diphemanil Methylsulfate
|
62-97-5 |
Diphemanil methylsulfate (NSC 41725; NSC-41725; Prantal; Talpran; Diphemanil mesylate) is a quaternary ammonium anticholinergic agent used for a variety of conditions such as pylorospasm,peptic ulcer, gastric hyperacidity, hypermotility in gastritis, and hyperhidrosis. |
|
V1167
|
Diphenidol HCl (Difenidol)
|
3254-89-5 |
Diphenidol HCl (Vontrol; Difenidol), the hydrochloride salt of diphenidol which is an antiemetic,is a potent antagonist of muscarinic M2 and M3 receptors usedas an antiemetic and as an antivertigo agent. |
|
V1159
|
Donepezil HCl (E2020)
|
120011-70-3 |
DonepezilHydrochloride (E2020; Aricept;E-2020), the hydrochloride salt ofDonepezil, is a noncompetitive,specific and potent AChE inhibitor for bAChE and hAChE with antiAlzheimers disease (AD) effects. |
|
V15400
|
Encenicline HCl salt (EVP6124; MT4666)
|
550999-74-1 |
Encenicline (EVP-6124; MT-4666) is a novel partial agonist of α7 nicotinic acetylcholine receptor. |